Government Adopts Landmark Strategy To Fight Alzheimer’s

It's clear that Alzheimer's quietly brews in the brain, killing off cells, for 10 years or more before symptoms appear, Dr. Reisa Sperling of Harvard Medical School told the meeting. She called that time period an important opportunity to try to stave off the disease, at least postponing the memory loss and other symptoms.

Already, 5.4 million Americans have Alzheimer's or related dementias. Barring a research breakthrough, those numbers will rise significantly by 2050, when up to 16 million Americans are projected to have Alzheimer's. Already, it's the sixth-leading killer, and there is no cure. Treatments only temporarily ease some symptoms.

Beyond the suffering, it's a budget-busting disease for Medicare, Medicaid and families. Caring for people with dementia will cost the U.S. $200 billion this year alone, and $1 trillion by 2050, the Alzheimer's Association estimates. Even that staggering figure doesn't fully reflect the toll. Sufferers lose the ability to do the simplest activities of daily life and can survive that way for a decade or more. Family members provide most of the care, unpaid, and too often their own health crumbles under the stress.

So the National Alzheimer's Plan, required by Congress, takes a two-pronged approach: focusing on future treatments plus help for families suffering today.

"There is a reinvigorated focus on this disease," Donald Moulds of HHS told The Associated Press.

Among the first steps:

• NIH's Collins on Tuesday will announce an $8 million study of an insulin nasal spray that pilot-testing suggests could help Alzheimer's. It's based on growing evidence that diabetes and Alzheimer's are related, damaging how the brain is fueled. The insulin nasal spray can reach the brain without affecting blood-sugar levels.
• Also, NIH was contributing $16 million to an international study of whether a treatment targeting amyloid, Alzheimer's hallmark brain plaque, could prevent the disease. The study will include people at highest risk, genetically, of the disease, including Americans and a unique group in Colombia.
• The government will begin offering training to doctors and other health providers on the best ways to care for patients and their families.
• A government website—http://www.alzheimers.gov—will offer one-stop information, in plain English about the disease and the challenges for families, including the financial burden. It also will link families to local resources near them, such as where to find the nearest adult day care, Moulds said.
• A $4 million advertising campaign this summer will spread word of the website. "Questions. When you're caring for a loved one with Alzheimer's, not a day goes by that you don't have them," the ad says. "The answers start here."

Beyond the initial steps, the plan lays out ways that federal and state governments plus private and nonprofit organizations can collaborate to battle Alzheimer's—from improving early diagnosis to creating more resources to help families with long-term care of their loved ones at home.